NOTE: This test is ONLY AVAILABLE TO AUSTRALIAN RESIDENTS.
Cardiovascular disease (CVD) is one of the leading causes of death worldwide. In the past decade, CVD has been the cause of over one-third of all premature deaths in Australia. The conventional risk factors for CVD include hypertension, dyslipidemia, smoking, and diabetes mellitus. However, in an individual, the presence of only one of these factors has a low positive predictive value. The most advanced strategy for coronary risk assessment is therefore to combine the information of several risk factors; a ‘multi-marker’ approach that enhances risk stratification.
Being one of the leading causes of death worldwide, more years of potential life before the age of 75 are lost due to this disease than any other human condition. Fortunately, over the past thirty years, significant progress has been made in the areas of diagnosis, prevention, and treatment of CVD. One of the most critical advances has been the identification of the major risk factors for CVD which arose from studies such as the Framingham Heart Study and the Seven Countries Study.
The conventional risk factors for CVD include hypertension, smoking, diabetes mellitus, hypercholesterolemia, hypertriglyceridemia, and low HDL cholesterol. However, in an individual, the presence of only one of these factors has a low positive predictive value. Furthermore, a significant number of cardiovascular events still occur in individuals without these established risk indicators. At present, the most advanced strategy for coronary risk assessment is therefore to combine the information of several risk factors. This multi-marker approach can enhance risk stratification, identifying those individuals with a moderate baseline risk who might benefit from aggressive risk reduction strategies. Not only are conventional risk factors assessed, but other CVD biomarkers such as lipoprotein (a), apolipoproteins A & B, homocysteine, fibrinogen, and C-reactive protein (CRP) are included.
The Comprehensive 2 option for the Cardiovascular Profile includes Liposcreen LDL-Subfraction analytes. Liposcreen separates and quantifies all lipoprotein sub-fractions including the ‘large’, less atherogenic LDL-1 and LDL-2 and the ‘small’, highly atherogenic LDL-3 to LDL-7. The test also measures VLDL and IDL cholesterol linked with type III dyslipidemia and associated hyperlipoproteinaemias.
Common Conditions:
- Hypercholesterolemia
- Insulin resistance
- Diabetes
- Cardiovascular disease
- Statin therapy
About the test kit:
- An authorized blood specimen order form that you take to your local accredited pathology for collection of your blood (Find a pathology near you here).
- A blood specimen test kit for the pathology to use to collect your blood sample
- Complete instructions for taking the test for you and the pathology
- Test results are sent to one of our professional health practitioners within 7 business days for evaluation. Our practitioners contact you with the results and recommendations on any findings via email, mail, or phone.
This test is a blood test kit. A test kit will be posted to you with full instructions including prepaid return postage to the laboratory. The following markers will be tested:
- Cholesterol
- Triglycerides
- HDL
- LDL
- ratios
- VLDL
- IDL
- LDL Subfractions (x7)
- Fasting Glucose
- Lipoprotein (a)
- Apolipoproteins A & B
- Homocysteine
- Fibrinogen
- C-reactive protein (CRP)
Turn around time 7-10 Business days
